Suppression question

[SnortFan <SnortFan () yahoo com>]

Hi All, 
     I know you can suppress a rule by either source or destination ip, but is there a way to suppress a rule from a 
known ip to another known ip? On one sensor I'm getting a excessive amount of hits on one preprocessor rule from a 
specific ip going to another specific ip.  I still want this rule to trigger but just not on this case from ip A to ip 
B. 

Thanks. 

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